2289-2292
| Discovery of Potent Nonpeptide Vitronectin Receptor ( V 3) Antagonists
Richard M. Keenan,
William H. Miller,
Chet Kwon,
Fadia E. Ali,
James F. Callahan,
Raul R. Calvo,
Shing-Mei Hwang,
Kenneth D. Kopple,
Catherine E. Peishoff,
James M. Samanen,
Angela S. Wong,
Chuan-Kui Yuan, and
William F. Huffman
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2293-2295
| Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of exo-2-(2'-Fluoro-5'-pyridinyl)-7-azabicyclo- [2.2.1]heptane: A New Positron Emission Tomography Ligand for Nicotinic Receptors
Feng Liang,
Hernán A. Navarro,
Philip Abraham,
Pravin Kotian,
Yu-Shin Ding,
Joanna Fowler,
Nora Volkow,
Michael J. Kuhar, and
F. Ivy Carroll
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2296-2303
| Structure-Activity Relationships for a Novel Series of Pyrido[2,3-d]pyrimidine Tyrosine Kinase Inhibitors
James M. Hamby,
Cleo J. C. Connolly,
Mel C. Schroeder,
R. Thomas Winters,
H. D. Hollis Showalter,
Robert L. Panek,
Terry C. Major,
Bronislawa Olsewski,
Michael J. Ryan,
Tawny Dahring,
Gina H. Lu,
Joan Keiser,
Aneesa Amar,
Cindy Shen,
Alan J. Kraker,
Veronika Slintak,
James M. Nelson,
David W. Fry,
Laura Bradford,
Hussein Hallak, and
Annette M. Doherty
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2304-2313
| Designing Combinatorial Library Mixtures Using a Genetic Algorithm
Robert D. Brown and
Yvonne C. Martin
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2314-2322
| Design, Synthesis, and Biological Evaluation of New Growth Inhibitors of Trypanosoma cruzi (Epimastigotes)
Andrea J. Schvartzapel,
Li Zhong,
Roberto Docampo,
Juan B. Rodriguez, and
Eduardo G. Gros
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2323-2334
| Synthesis of Analogs of 2-Methoxyestradiol with Enhanced Inhibitory Effects on Tubulin Polymerization and Cancer Cell Growth
Mark Cushman,
Hu-Ming He,
John A. Katzenellenbogen,
Ravi K. Varma,
Ernest Hamel,
Chii M. Lin,
Siya Ram, and
Yesh P. Sachdeva
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2335-2346
| 2-Cyclopropylindoloquinones and Their Analogues as Bioreductively Activated Antitumor Agents: Structure-Activity in Vitro and Efficacy in Vivo
Matthew A. Naylor,
Mohammed Jaffar,
John Nolan,
Miriam A. Stephens,
Susan Butler,
Kantilal B. Patel,
Steven A. Everett,
Gerald E. Adams, and
Ian J. Stratford
[Full Article -
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2347-2362
| A Novel Series of 2,5-Substituted Tryptamine Derivatives as Vascular 5HT1B/1D Receptor Antagonists
Gerard P. Moloney,
Alan D. Robertson,
Graeme R. Martin,
Steven MacLennan,
Neil Mathews,
Susan Dodsworth,
Pang Yih Sang,
Cameron Knight, and
Robert Glen
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2363-2373
| Synthesis and Anti-HIV-1 Activity of a Series of 1-Alkoxy-5-alkyl-6-(arylthio)uracils
Dae-Kee Kim,
Jongsik Gam,
Young-Woo Kim,
Jinsoo Lim,
Hun-Taek Kim, and
Key H. Kim
[Full Article -
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2374-2385
| 4-Heterocyclylpiperidines as Selective High-Affinity Ligands at the Human Dopamine D4 Receptor
Michael Rowley,
Ian Collins,
Howard B. Broughton,
William B. Davey,
Raymond Baker,
Frances Emms,
Rosemarie Marwood,
Shil Patel,
Smita Patel,
C. Ian Ragan,
Stephen B. Freedman,
Richard Ball, and
Paul D. Leeson
[Full Article -
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2386-2397
| Stabilized Analogs of Thymopentin. 1. 4,5-Ketomethylene Pseudopeptides
Joseph I. DeGraw,
Ronald G. Almquist,
Charles K. Hiebert,
William T. Colwell,
Jac Crase,
Takeshi Hayano,
Amrit K. Judd,
Linda Dousman,
R. Lane Smith,
William R. Waud, and
Itsuo Uchida
[Full Article -
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2398-2406
| Stabilized Analogs of Thymopentin. 2. 1,2- and 3,4-Ketomethylene Pseudopeptides
Joseph I. DeGraw,
Ronald G. Almquist,
Charles K. Hiebert,
Amrit K. Judd,
Linda Dousman,
R. Lane Smith,
William R. Waud, and
Itsuo Uchida
[Full Article -
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2407-2411
| Stabilized Analogs of Thymopentin. 3. Evaluation of Ketomethylene Pseudopeptides for Antiarthritic Properties
R. Lane Smith,
Linda Dousman,
William R. Waud, and
Joseph I. DeGraw
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2412-2423
| A Virtual Screening Approach Applied to the Search for Trypanothione Reductase Inhibitors
Dragos Horvath
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2424-2429
| Synthesis of Racemic 6,7,8,9-Tetrahydro-3-hydroxy-1H-1-benzazepine-2,5-diones as Antagonists of N-Methyl-D-aspartate (NMDA) and -Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid (AMPA) Receptors
Anthony P. Guzikowski,
Edward R. Whittemore,
Richard M. Woodward,
Eckard Weber, and
John F. W. Keana
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2430-2433
| Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 6. 2-Indol-3-yl- and 2-Azaindol-3-yl- dipyridodiazepinones
Terence A. Kelly,
Daniel W. McNeil,
Janice M. Rose,
Eva David,
Cheng-Kon Shih, and
Peter M. Grob
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2434-2434
| Emerging Drugs. The Prospect for Improved Medicines. Annual Executive Briefing. Volume Two. 1997 Edited by William C. Bowman, J. Desmond Fitzgerald, and John B. Taylor. Ashley Publications Ltd, London. 1997. x + 415 pp. 20.5 × 24 cm. ISSN 1361-9195. $640.00; $385.00 (pbk).
Staff
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